How much SAFE power

I am putting on my S-Trim and will post numbers in the weeks to come. Having said that I could use your input on the combo and safe power levels. I dont need 2 4 cyl. blocks!!
Looking for 425RWHP and 120mph+ traps.
Car trapped 110mph in current trim.

TFS Heads, polished and ported (stage 2)
Edlebrock performer intake (P and P)
Crane cam .533 -. 544, 270 - 276
306 ci, square decked block 30,000 miles
70mm t/b
75mm pro-m
42lb injectors, 255 in-tank with t-rex, afpr
S-Trim with 10psi boost expected (have 7" underdrive crank pulley and 2.87' (?), the 3 inch and on size larger pulley (sorry dont have specifics still new at the game)
Forged TRW pistons (stock compression)
2 5/8" LT headers and flowmasters.

Thanks !!!